The present study used a Double-ABCX model to explore parental stress in 48 British families with children with developmental disabilities and behavior problems in relation to certain child characteristics, resources, parents' perceptions and coping styles. Results indicated that the strongest predictors of parental stress were family coping style and parental internal locus of control. This study also examined parents' qualitative responses to questions concerning the stress they experience in dealing with friends, family, and doctors or other professionals. The emerging themes and clinical implications of these findings, methodological issues, and suggestions for future research are discussed.